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Allosteric inhibition of human exonuclease1 (hExo1) through a novel extended ß-sheet conformation.
Umar, Aminu Argungu; Liddell, Susan; Hussain, Rohanah; Siligardi, Giuliano; Harris, Gemma; Carr, Stephen; Asiani, Karishma; Gowers, Darren M; Odell, Mark; Scott, David J.
  • Umar AA; School of Biosciences, University of Nottingham Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom; Department of Biochemistry, Kebbi State University of Science and Technology, Aliero, P.M.B 1144, Birnin Kebbi, Nigeria. Electronic address: au.argungu@ksusta.edu.ng.
  • Liddell S; School of Biosciences, University of Nottingham Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom.
  • Hussain R; Diamond Light Source, Rutherford Appleton Laboratory, Oxfordshire OX11 0DE, United Kingdom.
  • Siligardi G; Diamond Light Source, Rutherford Appleton Laboratory, Oxfordshire OX11 0DE, United Kingdom.
  • Harris G; Research Complex at Harwell, Rutherford Appleton Laboratory, Oxfordshire OX11 0FA, United Kingdom.
  • Carr S; Research Complex at Harwell, Rutherford Appleton Laboratory, Oxfordshire OX11 0FA, United Kingdom.
  • Asiani K; School of Biosciences, University of Nottingham Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom.
  • Gowers DM; School of Biological Science, King Henry Building, King Henry 1(st) Street, Portsmouth, Hampshire PO1 2DY, United Kingdom.
  • Odell M; Department of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom.
  • Scott DJ; School of Biosciences, University of Nottingham Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom; Research Complex at Harwell, Rutherford Appleton Laboratory, Oxfordshire OX11 0FA, United Kingdom; ISIS Spallation Neutron and Muon source, Rutherford Appleton Laboratory, Oxfordshire OX
Biochim Biophys Acta Gen Subj ; 1864(12): 129730, 2020 12.
Article en En | MEDLINE | ID: mdl-32926959
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enzimas Reparadoras del ADN / Exodesoxirribonucleasas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enzimas Reparadoras del ADN / Exodesoxirribonucleasas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article