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Ibrutinib does not have clinically relevant interactions with oral contraceptives or substrates of CYP3A and CYP2B6.
de Jong, Jan; Mitselos, Anna; Jurczak, Wojciech; Cordoba, Raul; Panizo, Carlos; Wrobel, Tomasz; Dlugosz-Danecka, Monika; Jiao, James; Sukbuntherng, Juthamas; Ouellet, Daniele; Hellemans, Peter.
  • de Jong J; Clinical Pharmacology, Janssen Research & Development LLC, San Diego, CA, USA.
  • Mitselos A; Clinical Research Oncology, Janssen Research & Development LLC, Beerse, Belgium.
  • Jurczak W; Maria Sklodowska-Curie National Institute of Oncology, Krakow, Poland.
  • Cordoba R; Lymphoma Unit, Department of Hematology, Fundacion Jimenez Diaz University Hospital, Madrid, Spain.
  • Panizo C; Health Research Institute IIS-FJD, Madrid, Spain.
  • Wrobel T; START Madrid, Phase 1 Clinical Trials Unit, Madrid, Spain.
  • Dlugosz-Danecka M; Department of Hematology, Clínica Universidad de Navarra, Pamplona, Spain.
  • Jiao J; Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
  • Sukbuntherng J; Department and Clinic of Hematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
  • Ouellet D; Maria Sklodowska-Curie National Institute of Oncology, Krakow, Poland.
  • Hellemans P; Clinical Pharmacology, Janssen Research & Development LLC, Raritan, NJ, USA.
Pharmacol Res Perspect ; 8(5): e00649, 2020 10.
Article en En | MEDLINE | ID: mdl-32945596
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Adenina / Leucemia Linfocítica Crónica de Células B / Macroglobulinemia de Waldenström / Linfoma de Células B de la Zona Marginal / Anticonceptivos Orales / Linfoma de Células del Manto / Citocromo P-450 CYP3A / Citocromo P-450 CYP2B6 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Adenina / Leucemia Linfocítica Crónica de Células B / Macroglobulinemia de Waldenström / Linfoma de Células B de la Zona Marginal / Anticonceptivos Orales / Linfoma de Células del Manto / Citocromo P-450 CYP3A / Citocromo P-450 CYP2B6 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2020 Tipo del documento: Article