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Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS.
Dominguez, Sara; Varfolomeev, Eugene; Brendza, Robert; Stark, Kim; Tea, Joy; Imperio, Jose; Ngu, Hai; Earr, Timothy; Foreman, Oded; Webster, Joshua D; Easton, Amy; Vucic, Domagoj; Bingol, Baris.
  • Dominguez S; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Varfolomeev E; Department of Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Brendza R; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Stark K; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Tea J; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Imperio J; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Ngu H; Department of Pathology, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Earr T; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Foreman O; Department of Pathology, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Webster JD; Department of Pathology, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Easton A; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Vucic D; Department of Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, 94080, USA.
  • Bingol B; Department of Neuroscience, Genentech, Inc., South San Francisco, CA, 94080, USA. barisb@gene.com.
Cell Death Differ ; 28(3): 915-931, 2021 03.
Article en En | MEDLINE | ID: mdl-32994544
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Activadoras de GTPasa / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Neuronas Motoras Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Activadoras de GTPasa / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Neuronas Motoras Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article