Effective methylation triage of HPV positive women with abnormal cytology in a middle-income country.
Int J Cancer
; 148(6): 1383-1393, 2021 03 15.
Article
en En
| MEDLINE
| ID: mdl-33006394
ABSTRACT
The S5-methylation test, an alternative to cytology and HPV16/18 genotyping to triage high-risk HPV-positive (hrHPV+) women, has not been widely validated in low-middle-income countries (LMICs). We compared S5 to HPV16/18 and cytology to detect cervical intraepithelial neoplasia Grade 2 or worse (CIN2+) and CIN3+ in hrHPV+ women selected from a randomized pragmatic trial of 2661 Colombian women with an earlier-borderline abnormal cytology. We included all hrHPV+ CIN2 and CIN3+ cases (n = 183) age matched to 183 Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Displasia del Cuello del Útero
/
Neoplasias del Cuello Uterino
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Infecciones por Papillomavirus
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Detección Precoz del Cáncer
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Screening_studies
Límite:
Adult
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Aged
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Female
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Humans
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Middle aged
País como asunto:
America do sul
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Colombia
Idioma:
En
Año:
2021
Tipo del documento:
Article