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Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.
Shaw, Scott A; Vokits, Benjamin P; Dilger, Andrew K; Viet, Andrew; Clark, Charles G; Abell, Lynn M; Locke, Gregory A; Duke, Gerald; Kopcho, Lisa M; Dongre, Ashok; Gao, Ji; Krishnakumar, Arathi; Jusuf, Sutjano; Khan, Javed; Spronk, Steven A; Basso, Michael D; Zhao, Lei; Cantor, Glenn H; Onorato, Joelle M; Wexler, Ruth R; Duclos, Franck; Kick, Ellen K.
  • Shaw SA; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States. Electronic address: scott.shaw@bms.com.
  • Vokits BP; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Dilger AK; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Viet A; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Clark CG; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Abell LM; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Locke GA; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Duke G; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Kopcho LM; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Dongre A; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Gao J; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Krishnakumar A; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Jusuf S; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Khan J; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Spronk SA; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Basso MD; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Zhao L; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Cantor GH; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Onorato JM; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Wexler RR; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Duclos F; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
  • Kick EK; Bristol Myers Squibb Company, P.O. Box 5400, Princeton, NJ 08543-5400, United States.
Bioorg Med Chem ; 28(22): 115723, 2020 11 15.
Article en En | MEDLINE | ID: mdl-33007547
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Triazoles / Peroxidasa / Inhibidores Enzimáticos / Descubrimiento de Drogas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Triazoles / Peroxidasa / Inhibidores Enzimáticos / Descubrimiento de Drogas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article