The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.

Rosenberg, Eric M; Herrington, James; Rajasekaran, Deepa; Murphy, James W; Pantouris, Georgios; Lolis, Elias J

Rosenberg, Eric M; Herrington, James; Rajasekaran, Deepa; Murphy, James W; Pantouris, Georgios; Lolis, Elias J.

Rosenberg EM; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
Herrington J; Yale Center for Molecular Discovery, Yale West Campus, West Haven, CT 06516, USA.
Rajasekaran D; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
Murphy JW; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
Pantouris G; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
Lolis EJ; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.

Acta Crystallogr D Struct Biol ; 76(Pt 10): 1033-1049, 2020 Oct 01.

Article en En | MEDLINE | ID: mdl-33021505

Asunto(s)

Quimiocina CXCL13; Receptores CXCR5; Quimiocina CXCL13/química; Quimiocina CXCL13/metabolismo; Cristalografía por Rayos X; Humanos; Modelos Moleculares; Unión Proteica; Dominios Proteicos; Estructura Secundaria de Proteína; Receptores CXCR5/metabolismo

Palabras clave

CXCL13; CXCR5; G protein-coupled receptors; agonists; chemokines

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quimiocina CXCL13 / Receptores CXCR5 Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quimiocina CXCL13 / Receptores CXCR5 Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article