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The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity.
Di Cristo, Francesca; Calarco, Anna; Digilio, Filomena Anna; Sinicropi, Maria Stefania; Rosano, Camillo; Galderisi, Umberto; Melone, Mariarosa Anna Beatrice; Saturnino, Carmela; Peluso, Gianfranco.
  • Di Cristo F; Elleva Pharma S.R.L., via Pietro Castellino 111, 80131 Naples, Italy.
  • Calarco A; Research Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Digilio FA; Research Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Sinicropi MS; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Arcavacata di Rende, Italy.
  • Rosano C; Proteomics and Mass Spectrometry Unit, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132 Genova, Italy.
  • Galderisi U; Department of Experimental Medicine, Biotechnology and Molecular Biology Section, Luigi Vanvitelli Campania University, Vico Luigi De Crecchio 1, 80138 Naples, Italy.
  • Melone MAB; Department of Advanced Medical and Surgical Sciences, 2nd Division of Neurology, Center for Rare Diseases and InterUniversity Center for Research in Neurosciences, University of Campania "Luigi Vanvitelli", via Sergio Pansini 5, 80131 Naples, Italy.
  • Saturnino C; Department of Science, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
  • Peluso G; Research Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
Int J Mol Sci ; 21(19)2020 Oct 08.
Article en En | MEDLINE | ID: mdl-33050117
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Drosophila melanogaster / Miembro 5 de la Familia 22 de Transportadores de Solutos / Longevidad / Metilhidrazinas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Drosophila melanogaster / Miembro 5 de la Familia 22 de Transportadores de Solutos / Longevidad / Metilhidrazinas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article