Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-&#954;B Signaling Pathway.

Lim, Eun Yeong; Park, Joon; Kim, Yun Tai; Kim, Min Jung

Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-κB Signaling Pathway.

Lim, Eun Yeong; Park, Joon; Kim, Yun Tai; Kim, Min Jung.

Lim EY; Research group of Functional Food Materials, Korea Food Research Institute, 245, Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365, Korea.
Park J; Department of Food Biotechnology, Korea University of Science & Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Korea.
Kim YT; Research group of Functional Food Materials, Korea Food Research Institute, 245, Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365, Korea.
Kim MJ; Department of Food Biotechnology, Korea University of Science & Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Korea.

Molecules ; 25(20)2020 Oct 11.

Article en En | MEDLINE | ID: mdl-33050597

Asunto(s)

Imipramina/farmacología; FN-kappa B/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Antidepresivos/farmacología; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Regulación Neoplásica de la Expresión Génica; Humanos; Masculino; Células PC-3; Neoplasias de la Próstata Resistentes a la Castración/metabolismo; Cicatrización de Heridas/efectos de los fármacos

Palabras clave

antidepressants; imipramine; invasion; migration; prostate cancer

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Proteínas Proto-Oncogénicas c-akt / Imipramina Límite: Humans / Male Idioma: En Año: 2020 Tipo del documento: Article

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