IgE Epitope Profiling for Allergy Diagnosis and Therapy - Parallel Analysis of a Multitude of Potential Linear Epitopes Using a High Throughput Screening Platform.

Krause, Thorsten; Röckendorf, Niels; Meckelein, Barbara; Sinnecker, Heike; Schwager, Christian; Möckel, Stefanie; Jappe, Uta; Frey, Andreas

Krause, Thorsten; Röckendorf, Niels; Meckelein, Barbara; Sinnecker, Heike; Schwager, Christian; Möckel, Stefanie; Jappe, Uta; Frey, Andreas.

Krause T; Division of Mucosal Immunology and Diagnostics, Priority Area Asthma and Allergy, Research Center Borstel, Borstel, Germany.
Röckendorf N; Airway Research Center North, German Center for Lung Research (DZL), Borstel, Germany.
Meckelein B; Division of Mucosal Immunology and Diagnostics, Priority Area Asthma and Allergy, Research Center Borstel, Borstel, Germany.
Sinnecker H; Airway Research Center North, German Center for Lung Research (DZL), Borstel, Germany.
Schwager C; Division of Mucosal Immunology and Diagnostics, Priority Area Asthma and Allergy, Research Center Borstel, Borstel, Germany.
Möckel S; Airway Research Center North, German Center for Lung Research (DZL), Borstel, Germany.
Jappe U; Division of Mucosal Immunology and Diagnostics, Priority Area Asthma and Allergy, Research Center Borstel, Borstel, Germany.
Frey A; Airway Research Center North, German Center for Lung Research (DZL), Borstel, Germany.

Front Immunol ; 11: 565243, 2020.

Article en En | MEDLINE | ID: mdl-33117349

Asunto(s)

Desensibilización Inmunológica/métodos; Mapeo Epitopo/métodos; Epítopos de Linfocito B/metabolismo; Ensayos Analíticos de Alto Rendimiento/métodos; Inmunoglobulina E/metabolismo; Hipersensibilidad al Cacahuete/diagnóstico; Albuminas 2S de Plantas/genética; Albuminas 2S de Plantas/metabolismo; Adsorción; Antígenos de Plantas/genética; Antígenos de Plantas/metabolismo; Humanos; Microesferas; Biblioteca de Péptidos; Péptidos/genética; Péptidos/metabolismo; Unión Proteica

Palabras clave

allergy diagnosis; allergy therapy; combinatory peptide library; epitope detection; immunoglobulin E (IgE); one-bead-one-compound library

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inmunoglobulina E / Desensibilización Inmunológica / Mapeo Epitopo / Epítopos de Linfocito B / Hipersensibilidad al Cacahuete / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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