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REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
Chatterjee, Nimrat; Whitman, Matthew A; Harris, Cynthia A; Min, Sophia M; Jonas, Oliver; Lien, Evan C; Luengo, Alba; Vander Heiden, Matthew G; Hong, Jiyong; Zhou, Pei; Hemann, Michael T; Walker, Graham C.
  • Chatterjee N; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139; nimrat.chatterjee@med.uvm.edu gwalker@mit.edu.
  • Whitman MA; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
  • Harris CA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Min SM; Department of Chemistry, Duke University, Durham, NC 27708.
  • Jonas O; Department of Radiology, Brigham and Women's Hospital, Boston, MA 02215.
  • Lien EC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Luengo A; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139.
  • Vander Heiden MG; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139.
  • Hong J; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139.
  • Zhou P; Dana-Farber Cancer Institute, Boston, MA 02115.
  • Hemann MT; Department of Chemistry, Duke University, Durham, NC 27708.
  • Walker GC; Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710.
Proc Natl Acad Sci U S A ; 117(46): 28918-28921, 2020 11 17.
Article en En | MEDLINE | ID: mdl-33168727
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Inhibidores Enzimáticos / Neoplasias / Nitroquinolinas / Nucleotidiltransferasas Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Inhibidores Enzimáticos / Neoplasias / Nitroquinolinas / Nucleotidiltransferasas Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article