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The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth.
Song, Jianing; Zhu, Yuqin; Zu, Weidong; Duan, Chunqi; Xu, Junyu; Jiang, Fei; Wang, Xinren; Li, Shuwen; Liu, Chenhe; Gao, Qianqian; Li, Hongmei; Zhang, Yanmin; Tang, Weifang; Lu, Tao; Chen, Yadong.
  • Song J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Zhu Y; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Zu W; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Duan C; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Xu J; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Jiang F; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Wang X; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Li S; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Liu C; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Gao Q; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Li H; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Zhang Y; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Tang W; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China.
  • Lu T; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China. Electronic address: lutao@cpu.edu.cn.
  • Chen Y; School of Sciences, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China. Electronic address: ydchen@cpu.edu.cn.
Bioorg Med Chem ; 29: 115856, 2021 01 01.
Article en En | MEDLINE | ID: mdl-33199201
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolinas / Linfocitos T / Antiinflamatorios no Esteroideos / Proteínas Serina-Treonina Quinasas / Descubrimiento de Drogas Límite: Animals / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolinas / Linfocitos T / Antiinflamatorios no Esteroideos / Proteínas Serina-Treonina Quinasas / Descubrimiento de Drogas Límite: Animals / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article