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Small-molecule-induced polymerization triggers degradation of BCL6.
Slabicki, Mikolaj; Yoon, Hojong; Koeppel, Jonas; Nitsch, Lena; Roy Burman, Shourya S; Di Genua, Cristina; Donovan, Katherine A; Sperling, Adam S; Hunkeler, Moritz; Tsai, Jonathan M; Sharma, Rohan; Guirguis, Andrew; Zou, Charles; Chudasama, Priya; Gasser, Jessica A; Miller, Peter G; Scholl, Claudia; Fröhling, Stefan; Nowak, Radoslaw P; Fischer, Eric S; Ebert, Benjamin L.
  • Slabicki M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Yoon H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Koeppel J; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
  • Nitsch L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Roy Burman SS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Di Genua C; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Donovan KA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sperling AS; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
  • Hunkeler M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Tsai JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sharma R; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
  • Guirguis A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Zou C; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Chudasama P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gasser JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Miller PG; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Scholl C; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Fröhling S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Nowak RP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ebert BL; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Nature ; 588(7836): 164-168, 2020 12.
Article en En | MEDLINE | ID: mdl-33208943
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-bcl-6 / Polimerizacion / Proteolisis Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-bcl-6 / Polimerizacion / Proteolisis Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article