Identification of Persuasive Antiviral Natural Compounds for COVID-19 by Targeting Endoribonuclease NSP15: A Structural-Bioinformatics Approach.

Saeed, Mohd; Saeed, Amir; Alam, Md Jahoor; Alreshidi, Mousa

Saeed, Mohd; Saeed, Amir; Alam, Md Jahoor; Alreshidi, Mousa.

Saeed M; Department of Biology, College of Sciences, University of Ha'il, Ha'il 2440, Saudi Arabia.
Saeed A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Ha'il, Ha'il 2440, Saudi Arabia.
Alam MJ; Department of Biology, College of Sciences, University of Ha'il, Ha'il 2440, Saudi Arabia.
Alreshidi M; Department of Biology, College of Sciences, University of Ha'il, Ha'il 2440, Saudi Arabia.

Molecules ; 25(23)2020 Dec 01.

Article en En | MEDLINE | ID: mdl-33271751

Asunto(s)

Antivirales/farmacología; Endorribonucleasas/química; Ensayos Analíticos de Alto Rendimiento/métodos; Proteínas no Estructurales Virales/química; Antivirales/química; Antivirales/farmacocinética; Dominio Catalítico; Endorribonucleasas/metabolismo; Enlace de Hidrógeno; Interacciones Hidrofóbicas e Hidrofílicas; Ligandos; Simulación del Acoplamiento Molecular; Simulación de Dinámica Molecular; Proteínas no Estructurales Virales/metabolismo; Tratamiento Farmacológico de COVID-19

Palabras clave

NSP15; SARS-CoV-2; molecular dynamics; natural compounds; virtual screening

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Proteínas no Estructurales Virales / Endorribonucleasas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Año: 2020 Tipo del documento: Article

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