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The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks.
Blessing, Charlotte; Mandemaker, Imke Karlijn; Gonzalez-Leal, Claudia; Preisser, Julia; Schomburg, Adrian; Ladurner, Andreas Gerhard.
  • Blessing C; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany; International Max Planck Research School (IMPRS) for Molecular Life Sciences, 82152 Planegg-Martinsried, Germany.
  • Mandemaker IK; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany.
  • Gonzalez-Leal C; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany; International Max Planck Research School (IMPRS) for Molecular Life Sciences, 82152 Planegg-Martinsried, Germany.
  • Preisser J; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany.
  • Schomburg A; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany; Eisbach Bio GmbH, Am Klopferspitz 19, 82152 Planegg-Martinsried, Germany.
  • Ladurner AG; Department of Physiological Chemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 82152 Planegg-Martinsried, Germany; International Max Planck Research School (IMPRS) for Molecular Life Sciences, 82152 Planegg-Martinsried, Germany; Eisbach Bio GmbH, Am Klopferspitz 19, 82152 Planegg-M
Mol Cell ; 80(5): 862-875.e6, 2020 12 03.
Article en En | MEDLINE | ID: mdl-33275888
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Poli(ADP-Ribosa) Polimerasas / ADN Helicasas / Proteínas de Unión al ADN / Roturas del ADN de Cadena Simple / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Neoplasias Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Poli(ADP-Ribosa) Polimerasas / ADN Helicasas / Proteínas de Unión al ADN / Roturas del ADN de Cadena Simple / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Neoplasias Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article