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Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.
Werthmann, Ruth C; Tzouros, Manuel; Lamerz, Jens; Augustin, Angélique; Fritzius, Thorsten; Trovò, Luca; Stawarski, Michal; Raveh, Adi; Diener, Catherine; Fischer, Christophe; Gassmann, Martin; Lindemann, Lothar; Bettler, Bernhard.
  • Werthmann RC; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Tzouros M; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Lamerz J; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Augustin A; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Fritzius T; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Trovò L; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Stawarski M; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Raveh A; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Diener C; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Fischer C; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Gassmann M; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Lindemann L; Roche Pharmaceutical Research and Early Development, Discovery Neuroscience, Neuroscience and Rare Diseases (NRD) (LL, CD, CF), Pharmaceutical Sciences, Biomarkers, Bioinformatics and Omics & Pathology (MT, JL, AA), Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Bettler B; Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland. Electronic address: bernhard.bettler@unibas.ch.
Neuropharmacology ; 190: 108426, 2021 06 01.
Article en En | MEDLINE | ID: mdl-33279506
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Glutamato Metabotrópico / Receptor del Glutamato Metabotropico 5 / Hipocampo / Neuronas Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Glutamato Metabotrópico / Receptor del Glutamato Metabotropico 5 / Hipocampo / Neuronas Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article