Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler.

Liwocha, Joanna; Krist, David T; van der Heden van Noort, Gerbrand J; Hansen, Fynn M; Truong, Vinh H; Karayel, Ozge; Purser, Nicholas; Houston, Daniel; Burton, Nicole; Bostock, Mark J; Sattler, Michael; Mann, Matthias; Harrison, Joseph S; Kleiger, Gary; Ovaa, Huib; Schulman, Brenda A

Liwocha, Joanna; Krist, David T; van der Heden van Noort, Gerbrand J; Hansen, Fynn M; Truong, Vinh H; Karayel, Ozge; Purser, Nicholas; Houston, Daniel; Burton, Nicole; Bostock, Mark J; Sattler, Michael; Mann, Matthias; Harrison, Joseph S; Kleiger, Gary; Ovaa, Huib; Schulman, Brenda A.

Liwocha J; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.
Krist DT; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.
van der Heden van Noort GJ; Carle Illinois College of Medicine, Champaign, IL, USA.
Hansen FM; Oncode Institute and Department of Cell and Chemical Biology, Chemical Immunology, Leiden University Medical Centre, Leiden, the Netherlands.
Truong VH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Karayel O; Department of Chemistry, University of the Pacific, Stockton, CA, USA.
Purser N; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Houston D; Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Burton N; Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Bostock MJ; Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Sattler M; Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technical University of Munich, Garching, Germany.
Mann M; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Harrison JS; Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technical University of Munich, Garching, Germany.
Kleiger G; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Ovaa H; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Schulman BA; Department of Chemistry, University of the Pacific, Stockton, CA, USA.

Nat Chem Biol ; 17(3): 272-279, 2021 03.

Article en En | MEDLINE | ID: mdl-33288957

Asunto(s)

Lisina/química; Proteína NEDD8/química; Poliubiquitina/química; Procesamiento Proteico-Postraduccional; Ubiquitina/química; Sitios de Unión; Clonación Molecular; Cristalografía por Rayos X; Escherichia coli/genética; Escherichia coli/metabolismo; Expresión Génica; Vectores Genéticos/química; Vectores Genéticos/metabolismo; Humanos; Cinética; Lisina/metabolismo; Modelos Moleculares; Proteína NEDD8/genética; Proteína NEDD8/metabolismo; Proteínas Nucleares/química; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Poliubiquitina/genética; Poliubiquitina/metabolismo; Unión Proteica; Dominios y Motivos de Interacción de Proteínas; Estructura Secundaria de Proteína; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Especificidad por Sustrato; Factores de Transcripción/química; Factores de Transcripción/genética; Factores de Transcripción/metabolismo; Ubiquitina/genética; Ubiquitina/metabolismo; Enzimas Ubiquitina-Conjugadoras/química; Enzimas Ubiquitina-Conjugadoras/genética; Enzimas Ubiquitina-Conjugadoras/metabolismo; Ubiquitinación

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Ubiquitina / Poliubiquitina / Proteína NEDD8 / Lisina Tipo de estudio: Prognostic_studies Idioma: En Año: 2021 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google