Surgical ischemia and reperfusion of the spinal cord effect on specific perfusion and neurological outcome. Experimental study / A sebészi gerincvelo ischemia és reperfusio hatása a specifikus átáramlásra és a neurológiai következményekre
Magy Seb
; 73(4): 153-159, 2020 Dec 12.
Article
en Hu
| MEDLINE
| ID: mdl-33310918
ABSTRACT
Clamping of the thoracoabdominal aorta reduces perfusion of the spinal cord significantly, which clinically may present as paraparesis or paraplegia devastating and unpredictable complications of open thoracoabdominal aortic surgery. Introduction of monitoring of evoked potentials and/or biochemical markers, methods increasing distal arterial pressure, indirect procedures enhancing residual flow (like liquor drainage), drugs, and use of hypothermia contributed to achieve better outcome. Preconditioning of spinal cord circulation is also a promising method. New endovascular techniques for thoracoabdominal aortic aneurysms and dissections reduced surgical trauma significantly. Despite all these progressions spinal cord ischemic damage is still a significant risk. To address this problem we carried out an experimental work using a canine model focusing on the protective effect of distal arterial perfusion, spinal fluid drainage, and their combination in a one hour setting of thoracoabdominal aortic clamping. In this paper we publish our data of circulatory and specific perfusion parameters of the spinal cord during and after declamping in correlation of final neurologic outcome.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Paraplejía
/
Médula Espinal
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Aneurisma de la Aorta Torácica
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Aneurisma de la Aorta Abdominal
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Procedimientos Endovasculares
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Isquemia
Límite:
Animals
Idioma:
Hu
Año:
2020
Tipo del documento:
Article