[Alterations of regional homogeneity in patients with psychogenic erectile dysfunction: A study by resting-state functional MRI].
Zhonghua Nan Ke Xue
; 26(2): 118-122, 2020 Feb.
Article
en Zh
| MEDLINE
| ID: mdl-33346413
ABSTRACT
OBJECTIVE:
To study the correlation between the brain regional homogeneity (ReHo) features and the clinical characteristics of the patients with psychogenic erectile dysfunction (pED).METHODS:
Using IIEF-5 and the Self-Esteem and Relationship (SEAR) questionnaire, we evaluated the erectile function and psychosocial status of 32 pED patients and 28 healthy male subjects. Then, we compared the regional brain activity between the patients and healthy controls by resting-state functional magnetic resonance imaging (RS-fMRI) and the ReHo method, analyzed the correlation of the ReHo value of the altered brain regions with the results of IIEF-5 and SEAR questionnaire investigation, and explored the relationship between the ReHo features and the symptoms of the pED patients.RESULTS:
Compared with the healthy male subjects, the pED patients obtained significantly lower IIEF-5 scores (22.21 ± 0.98 vs 13.97 ± 3.60, P < 0.01) and SEAR scores (61.92 ± 3.73 vs 37.58 ± 7.96, P < 0.01), a higher ReHo value of the left lateral cerebellum, and a lower ReHo value of the right precentral gyrus. The ReHo value of the left lateral cerebellum was correlated negatively with the IIEF-5 scores (r= ï¼0.51, P < 0.01) and SEAR scores (r = ï¼0.54, P < 0.01), while that of the right precentral gyrus positively with the IIEF-5 scores (r = 0.57, P < 0.01) and SEAR scores (r = 0.66, P < 0.01).CONCLUSIONS:
Patients with pED had lateral cerebellum-mediated abnormal sensory integration and precentral gyrus-related dysfunction of motor imagery and motor execution.Palabras clave
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Banco de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Disfunción Eréctil
Tipo de estudio:
Observational_studies
/
Qualitative_research
Límite:
Humans
/
Male
Idioma:
Zh
Año:
2020
Tipo del documento:
Article