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PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
Thomsen, Majken B; Ferreira, Sara A; Schacht, Anna C; Jacobsen, Jan; Simonsen, Mette; Betzer, Cristine; Jensen, Poul H; Brooks, David J; Landau, Anne M; Romero-Ramos, Marina.
  • Thomsen MB; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Med
  • Ferreira SA; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark.
  • Schacht AC; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark.
  • Jacobsen J; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark.
  • Simonsen M; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark.
  • Betzer C; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark.
  • Jensen PH; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark.
  • Brooks DJ; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
  • Landau AM; Department of Nuclear Medicine and PET Center, Institute of Clinical Medicine, Aarhus University and Hospital, Aarhus, Denmark; Translational Neuropsychiatry Unit, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Romero-Ramos M; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark. Electronic address: mrr@biomed.au.dk.
Neurobiol Dis ; 149: 105229, 2021 02.
Article en En | MEDLINE | ID: mdl-33352233
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Progresión de la Enfermedad / Cuerpo Estriado / Tomografía de Emisión de Positrones / Alfa-Sinucleína / Neuronas Dopaminérgicas / Agregado de Proteínas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Progresión de la Enfermedad / Cuerpo Estriado / Tomografía de Emisión de Positrones / Alfa-Sinucleína / Neuronas Dopaminérgicas / Agregado de Proteínas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article