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Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition.
Carter, Bing Z; Mak, Po Yee; Tao, Wenjing; Warmoes, Marc; Lorenzi, Philip L; Mak, Duncan; Ruvolo, Vivian; Tan, Lin; Cidado, Justin; Drew, Lisa; Andreeff, Michael.
  • Carter BZ; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston. bicarter@mdanderson.org.
  • Mak PY; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston.
  • Tao W; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston.
  • Warmoes M; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston.
  • Lorenzi PL; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston.
  • Mak D; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston.
  • Ruvolo V; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston.
  • Tan L; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston.
  • Cidado J; Bioscience Oncology RandD, AstraZeneca, Boston.
  • Drew L; Bioscience Oncology RandD, AstraZeneca, Boston.
  • Andreeff M; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston. mandreef@mdanderson.org.
Haematologica ; 107(1): 58-76, 2022 01 01.
Article en En | MEDLINE | ID: mdl-33353284
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogénicas c-bcl-2 / Proteína 1 de la Secuencia de Leucemia de Células Mieloides Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogénicas c-bcl-2 / Proteína 1 de la Secuencia de Leucemia de Células Mieloides Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article