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Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Nav 1.2 expression.
Eaton, Muriel; Zhang, Jingliang; Ma, Zhixiong; Park, Anthony C; Lietzke, Emma; Romero, Chloé M; Liu, Yushuang; Coleman, Emily R; Chen, Xiaoling; Xiao, Tiange; Que, Zhefu; Lai, Shirong; Wu, Jiaxiang; Lee, Ji Hea; Palant, Sophia; Nguyen, Huynhvi P; Huang, Zhuo; Skarnes, William C; Koss, Wendy A; Yang, Yang.
  • Eaton M; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Zhang J; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Ma Z; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Park AC; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Lietzke E; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Romero CM; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Liu Y; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Coleman ER; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Chen X; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Xiao T; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Que Z; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Lai S; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Wu J; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Lee JH; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Palant S; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Nguyen HP; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Huang Z; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Skarnes WC; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Koss WA; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, USA.
  • Yang Y; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
Genes Brain Behav ; 20(4): e12725, 2021 04.
Article en En | MEDLINE | ID: mdl-33369088
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canales de Sodio Activados por Voltaje / Canal de Sodio Activado por Voltaje NAV1.2 / Mutación Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canales de Sodio Activados por Voltaje / Canal de Sodio Activado por Voltaje NAV1.2 / Mutación Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article