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What Is T+? A Gordian Knot of Tracers, Thresholds, and Topographies.
Villemagne, Victor L; Lopresti, Brian J; Doré, Vincent; Tudorascu, Dana; Ikonomovic, Milos D; Burnham, Samantha; Minhas, Davneet; Pascoal, Tharick A; Mason, N Scott; Snitz, Beth; Aizenstein, Howard; Mathis, Chester A; Lopez, Oscar; Rowe, Christopher C; Klunk, William E; Cohen, Ann D.
  • Villemagne VL; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania victor.villemagne@pitt.edu.
  • Lopresti BJ; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Doré V; School of Medical and Health Sciences, Edith Cowan University, Perth, Washington, Australia.
  • Tudorascu D; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Ikonomovic MD; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Victoria, Australia.
  • Burnham S; CSIRO Health and Biosecurity, Melbourne, Victoria, Australia.
  • Minhas D; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Pascoal TA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Mason NS; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
  • Snitz B; CSIRO Health and Biosecurity, Melbourne, Victoria, Australia.
  • Aizenstein H; Center for Alzheimer Research and Treatment, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, Massachusetts.
  • Mathis CA; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Lopez O; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Rowe CC; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Klunk WE; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Cohen AD; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
J Nucl Med ; 62(5): 614-619, 2021 05 10.
Article en En | MEDLINE | ID: mdl-33384320
ABSTRACT
In this review we examine, in the context of the amyloid, tau, and neurodegeneration framework, the available evidence and potential alternatives on how to establish tau positivity (T+) for multiple tau-imaging tracers in order to reach a consensus on normal and abnormal tau imaging values that can be universally implemented in clinical research and therapeutic trials.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trazadores Radiactivos / Proteínas tau Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trazadores Radiactivos / Proteínas tau Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article