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2,3,5,6-Tetramethylpyrazine protects retinal photoreceptors against endoplasmic reticulum stress by modulating ATF4-mediated inhibition of PRP aggregation.
Huang, Hao; Zhu, Xiaobo; Cheng, Hao; Kuang, Xielan; Long, Chongde; Deng, Xizhi; Zou, Yuxiu; Zhang, Han; Xing, Yue; Ling, Xiangtian; Wang, Renchun; Tang, Han; Du, Han; Shi, Kangpei; Wang, Lei; Yan, Jianhua; Shen, Huangxuan.
  • Huang H; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Zhu X; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Cheng H; Department of Ophthalmology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Kuang X; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Long C; Biobank of Eye, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Deng X; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Zou Y; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Zhang H; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Xing Y; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Ling X; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Wang R; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Tang H; The Second Clinical Medicine School of Lanzhou University, Lanzhou, 730000, China.
  • Du H; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Shi K; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Wang L; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Yan J; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
  • Shen H; State Key laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
J Mol Med (Berl) ; 99(3): 383-402, 2021 03.
Article en En | MEDLINE | ID: mdl-33409554
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Degeneración Retiniana / Células Fotorreceptoras Retinianas Conos / Factor de Transcripción Activador 4 / Estrés del Retículo Endoplásmico / Agregación Patológica de Proteínas / Agregado de Proteínas / Proteínas Priónicas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Degeneración Retiniana / Células Fotorreceptoras Retinianas Conos / Factor de Transcripción Activador 4 / Estrés del Retículo Endoplásmico / Agregación Patológica de Proteínas / Agregado de Proteínas / Proteínas Priónicas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article