HLA typing in birdshot chorioretinopathy.

Priem, H A; Kijlstra, A; Noens, L; Baarsma, G S; De Laey, J J; Oosterhuis, J A

Priem, H A; Kijlstra, A; Noens, L; Baarsma, G S; De Laey, J J; Oosterhuis, J A.

Priem HA; Department of Ophthalmology, University of Gent, Belgium.

Am J Ophthalmol ; 105(2): 182-5, 1988 Feb 15.

Article en En | MEDLINE | ID: mdl-3341436

ABSTRACT

ABSTRACT

We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).

Asunto(s)

Antígenos HLA/análisis; Antígenos HLA-A; Antígenos HLA-B; Enfermedades de la Retina/diagnóstico; Enfermedades de la Úvea/diagnóstico; Coroides/inmunología; Antígenos HLA/genética; Antígeno HLA-B44; Prueba de Histocompatibilidad; Humanos; Enfermedades de la Retina/genética; Enfermedades de la Retina/inmunología; Factores de Riesgo; Enfermedades de la Úvea/genética; Enfermedades de la Úvea/inmunología

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Banco de datos: MEDLINE Asunto principal: Enfermedades de la Retina / Enfermedades de la Úvea / Antígenos HLA-A / Antígenos HLA-B / Antígenos HLA Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 1988 Tipo del documento: Article

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