Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies.
Neural Plast
; 2020: 8856621, 2020.
Article
en En
| MEDLINE
| ID: mdl-33414823
ABSTRACT
Background:
Physical exercise (PE) has been associated with increase neuroplasticity, neurotrophic factors, and improvements in brain function.Objective:
To evaluate the effects of different PE protocols on neuroplasticity components and brain function in a human and animal model.Methods:
We conducted a systematic review process from November 2019 to January 2020 of the following databases PubMed, ScienceDirect, SciELO, LILACS, and Scopus. A keyword combination referring to PE and neuroplasticity was included as part of a more thorough search process. From an initial number of 20,782 original articles, after reading the titles and abstracts, twenty-one original articles were included. Two investigators evaluated the abstract, the data of the study, the design, the sample size, the participant characteristics, and the PE protocol.Results:
PE increases neuroplasticity via neurotrophic factors (BDNF, GDNF, and NGF) and receptor (TrkB and P75NTR) production providing improvements in neuroplasticity, and cognitive function (learning and memory) in human and animal models.Conclusion:
PE was effective for increasing the production of neurotrophic factors, cell growth, and proliferation, as well as for improving brain functionality.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
/
Cognición
/
Aprendizaje
/
Memoria
/
Plasticidad Neuronal
Tipo de estudio:
Prognostic_studies
/
Systematic_reviews
Límite:
Animals
/
Humans
Idioma:
En
Año:
2020
Tipo del documento:
Article