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Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.
Gromeier, Matthias; Brown, Michael C; Zhang, Gao; Lin, Xiang; Chen, Yeqing; Wei, Zhi; Beaubier, Nike; Yan, Hai; He, Yiping; Desjardins, Annick; Herndon, James E; Varn, Frederick S; Verhaak, Roel G; Zhao, Junfei; Bolognesi, Dani P; Friedman, Allan H; Friedman, Henry S; McSherry, Frances; Muscat, Andrea M; Lipp, Eric S; Nair, Smita K; Khasraw, Mustafa; Peters, Katherine B; Randazzo, Dina; Sampson, John H; McLendon, Roger E; Bigner, Darell D; Ashley, David M.
  • Gromeier M; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Brown MC; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Zhang G; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Lin X; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Chen Y; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Wei Z; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Beaubier N; Department of Computer Science at the New Jersey Institute of Technology, Newark, NJ, 07102, USA.
  • Yan H; Department of Computer Science at the New Jersey Institute of Technology, Newark, NJ, 07102, USA.
  • He Y; Department of Computer Science at the New Jersey Institute of Technology, Newark, NJ, 07102, USA.
  • Desjardins A; Tempus Labs, Inc., Chicago, IL, 60654, USA.
  • Herndon JE; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Varn FS; Department of Pathology, Duke University Medical Center, Durham, NC, 27710, USA.
  • Verhaak RG; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Zhao J; Department of Pathology, Duke University Medical Center, Durham, NC, 27710, USA.
  • Bolognesi DP; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Friedman AH; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Friedman HS; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • McSherry F; Department of Biostatistics, Duke University Medical Center, Durham, NC, 27710, USA.
  • Muscat AM; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
  • Lipp ES; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
  • Nair SK; Department of Systems Biology at Columbia University, New York, NY, 10032, USA.
  • Khasraw M; Department of Surgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Peters KB; Istari Oncology Inc., Morrisville, NC, 27560, USA.
  • Randazzo D; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Sampson JH; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • McLendon RE; Department of Neurosurgery, Duke University Medical Center, Durham, NC, 27710, USA.
  • Bigner DD; The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, NC, USA.
  • Ashley DM; Department of Biostatistics, Duke University Medical Center, Durham, NC, 27710, USA.
Nat Commun ; 12(1): 352, 2021 01 13.
Article en En | MEDLINE | ID: mdl-33441554
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Viroterapia Oncolítica / Inmunoterapia / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Viroterapia Oncolítica / Inmunoterapia / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article