Inhibition of liver tumor cell colonization in two animal tumor models by lectin blocking with D-galactose or arabinogalactan.
Clin Exp Metastasis
; 6(2): 115-20, 1988.
Article
en En
| MEDLINE
| ID: mdl-3345610
ABSTRACT
Repeated administration of the hepatic lectin blocking agents D-galactose or arabinogalactan completely prevented the settling of metastatic cells of sarcoma L-1 tumor in the liver of Balb/c mice and greatly reduced the colonization process of highly metastatic ESb lymphoma cells of the liver of DBA/2 mice. Therefore, when hepatic lectins were blocked with competitive glycoconjugates, tumor cell colonization of the liver could be prevented in two different model systems.
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Banco de datos:
MEDLINE
Asunto principal:
Sarcoma Experimental
/
Leucemia Experimental
/
Leucemia L5178
/
Galactanos
/
Galactosa
/
Lectinas
/
Hígado
/
Neoplasias Hepáticas Experimentales
Límite:
Animals
Idioma:
En
Año:
1988
Tipo del documento:
Article