Pancreatic cancer is associated with aberrant monocyte function and successive differentiation into macrophages with inferior anti-tumour characteristics.

Juusola, Matilda; Kuuliala, Krista; Kuuliala, Antti; Mustonen, Harri; Vähä-Koskela, Markus; Puolakkainen, Pauli; Seppänen, Hanna

Juusola, Matilda; Kuuliala, Krista; Kuuliala, Antti; Mustonen, Harri; Vähä-Koskela, Markus; Puolakkainen, Pauli; Seppänen, Hanna.

Juusola M; Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Translational Cancer Medicine Research Program, University of Helsinki, Helsinki, Finland. Electronic address: matilda.juusola@helsinki.fi.
Kuuliala K; Department of Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kuuliala A; Department of Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Mustonen H; Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Vähä-Koskela M; Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.
Puolakkainen P; Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Translational Cancer Medicine Research Program, University of Helsinki, Helsinki, Finland.
Seppänen H; Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Translational Cancer Medicine Research Program, University of Helsinki, Helsinki, Finland.

Pancreatology ; 21(2): 397-405, 2021 Mar.

Article en En | MEDLINE | ID: mdl-33461933

Asunto(s)

Diferenciación Celular/fisiología; Macrófagos/fisiología; Monocitos/fisiología; Neoplasias Pancreáticas/patología; Anciano; Anciano de 80 o más Años; Biomarcadores/sangre; Línea Celular Tumoral; Movimiento Celular; Técnicas de Cocultivo; Citocinas/metabolismo; Femenino; Regulación de la Expresión Génica; Humanos; Inflamación; Masculino; Persona de Mediana Edad; Monocitos/efectos de los fármacos; Transducción de Señal

Palabras clave

Immunosuppression; Inflammation; Macrophages; Monocytes; Pancreatic neoplasms

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Monocitos / Diferenciación Celular / Macrófagos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article

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