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Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei.
Zhang, Zhongsheng; Barros-Álvarez, Ximena; Gillespie, J Robert; Ranade, Ranae M; Huang, Wenlin; Shibata, Sayaka; Molasky, Nora M R; Faghih, Omeed; Mushtaq, Aisha; Choy, Robert K M; de Hostos, Eugenio; Hol, Wim G J; Verlinde, Christophe L M J; Buckner, Frederick S; Fan, Erkang.
  • Zhang Z; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Barros-Álvarez X; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Gillespie JR; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Ranade RM; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Huang W; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Shibata S; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Molasky NMR; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Faghih O; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Mushtaq A; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Choy RKM; PATH , San Francisco , CA 94108 , USA.
  • de Hostos E; PATH , San Francisco , CA 94108 , USA.
  • Hol WGJ; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Verlinde CLMJ; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
  • Buckner FS; Department of Medicine , Division of Allergy & Infectious Disease , Center for Emerging & Re-emerging Infectious Disease (CERID) , University of Washington , Seattle , WA 98109 , USA . Email: fbuckner@uw.edu.
  • Fan E; Department of Biochemistry , University of Washington , Seattle , WA 98195 , USA . Email: erkang@uw.edu.
RSC Med Chem ; 11(8): 885-895, 2020 Aug 01.
Article en En | MEDLINE | ID: mdl-33479683
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2020 Tipo del documento: Article