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Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.
Tadros, Rafik; Francis, Catherine; Xu, Xiao; Vermeer, Alexa M C; Harper, Andrew R; Huurman, Roy; Kelu Bisabu, Ken; Walsh, Roddy; Hoorntje, Edgar T; Te Rijdt, Wouter P; Buchan, Rachel J; van Velzen, Hannah G; van Slegtenhorst, Marjon A; Vermeulen, Jentien M; Offerhaus, Joost Allard; Bai, Wenjia; de Marvao, Antonio; Lahrouchi, Najim; Beekman, Leander; Karper, Jacco C; Veldink, Jan H; Kayvanpour, Elham; Pantazis, Antonis; Baksi, A John; Whiffin, Nicola; Mazzarotto, Francesco; Sloane, Geraldine; Suzuki, Hideaki; Schneider-Luftman, Deborah; Elliott, Paul; Richard, Pascale; Ader, Flavie; Villard, Eric; Lichtner, Peter; Meitinger, Thomas; Tanck, Michael W T; van Tintelen, J Peter; Thain, Andrew; McCarty, David; Hegele, Robert A; Roberts, Jason D; Amyot, Julie; Dubé, Marie-Pierre; Cadrin-Tourigny, Julia; Giraldeau, Geneviève; L'Allier, Philippe L; Garceau, Patrick; Tardif, Jean-Claude; Boekholdt, S Matthijs; Lumbers, R Thomas.
  • Tadros R; Cardiovascular Genetics Center, Montreal Heart Institute, Faculty of Medicine, Université de Montréal, Montreal, Québec, Canada. rafik.tadros@umontreal.ca.
  • Francis C; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. rafik.tadros@umontreal.ca.
  • Xu X; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Vermeer AMC; National Heart and Lung Institute, Imperial College London, London, UK.
  • Harper AR; MRC London Institute of Medical Sciences, Imperial College London, London, UK.
  • Huurman R; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Kelu Bisabu K; Department of Clinical Genetics, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Walsh R; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART).
  • Hoorntje ET; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Te Rijdt WP; Wellcome Centre for Human Genetics, Oxford, UK.
  • Buchan RJ; Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • van Velzen HG; Cardiovascular Genetics Center, Montreal Heart Institute, Faculty of Medicine, Université de Montréal, Montreal, Québec, Canada.
  • van Slegtenhorst MA; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Vermeulen JM; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Offerhaus JA; Netherlands Heart Institute, Utrecht, the Netherlands.
  • Bai W; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • de Marvao A; Netherlands Heart Institute, Utrecht, the Netherlands.
  • Lahrouchi N; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Beekman L; National Heart and Lung Institute, Imperial College London, London, UK.
  • Karper JC; Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Veldink JH; Department of Clinical Genetics, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Kayvanpour E; Department of Psychiatry, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Pantazis A; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Baksi AJ; Data Science Institute, Imperial College London, London, UK.
  • Whiffin N; Department of Brain Sciences and UK Dementia Research Institute at Imperial College London, Hammersmith Hospital, Imperial College London, London, UK.
  • Mazzarotto F; MRC London Institute of Medical Sciences, Imperial College London, London, UK.
  • Sloane G; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Suzuki H; Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Schneider-Luftman D; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Elliott P; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Richard P; Institute for Cardiomyopathies, Heidelberg Heart Center, University of Heidelberg, Heidelberg, Germany.
  • Ader F; DZHK (German Center for Cardiovascular Research), Berlin, Germany.
  • Villard E; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Lichtner P; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Meitinger T; National Heart and Lung Institute, Imperial College London, London, UK.
  • Tanck MWT; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • van Tintelen JP; National Heart and Lung Institute, Imperial College London, London, UK.
  • Thain A; MRC London Institute of Medical Sciences, Imperial College London, London, UK.
  • McCarty D; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Hegele RA; National Heart and Lung Institute, Imperial College London, London, UK.
  • Roberts JD; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Amyot J; Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy.
  • Dubé MP; Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, UK.
  • Cadrin-Tourigny J; National Heart and Lung Institute, Imperial College London, London, UK.
  • Giraldeau G; Department of Brain Sciences and UK Dementia Research Institute at Imperial College London, Hammersmith Hospital, Imperial College London, London, UK.
  • L'Allier PL; Department of Cardiovascular Medicine, Tohoku University Hospital, Seiryo, Aoba, Sendai, Japan.
  • Garceau P; Tohoku Medical Megabank Organization, Tohoku University, Seiryo, Aoba, Sendai, Japan.
  • Tardif JC; The Francis Crick Institute, London, UK.
  • Boekholdt SM; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
  • Lumbers RT; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Nat Genet ; 53(2): 128-134, 2021 02.
Article en En | MEDLINE | ID: mdl-33495596
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cardiomiopatía Dilatada Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cardiomiopatía Dilatada Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article