Most colitis associated carcinomas lack expression of LGR5: a preliminary study with implications for unique pathways of carcinogenesis compared to sporadic colorectal carcinoma.

Iwaya, Mai; Ota, Hiroyoshi; Nakajima, Tomoyuki; Uehara, Takeshi; Riddell, Robert; Conner, James

Iwaya, Mai; Ota, Hiroyoshi; Nakajima, Tomoyuki; Uehara, Takeshi; Riddell, Robert; Conner, James.

Iwaya M; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada. mkatou@shinshu-u.ac.jp.
Ota H; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. mkatou@shinshu-u.ac.jp.
Nakajima T; Department of Laboratory Medicine, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, Nagano, Japan. mkatou@shinshu-u.ac.jp.
Uehara T; Department of Clinical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan.
Riddell R; Department of Laboratory Medicine, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, Nagano, Japan.
Conner J; Department of Laboratory Medicine, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, Nagano, Japan.

BMC Cancer ; 21(1): 119, 2021 Feb 04.

Article en En | MEDLINE | ID: mdl-33541282

Asunto(s)

Adenocarcinoma/patología; Biomarcadores de Tumor/metabolismo; Carcinogénesis/patología; Colitis/complicaciones; Neoplasias Colorrectales/patología; Receptores Acoplados a Proteínas G/metabolismo; Adenocarcinoma/etiología; Adenocarcinoma/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Biomarcadores de Tumor/genética; Carcinogénesis/metabolismo; Estudios de Casos y Controles; Neoplasias Colorrectales/etiología; Neoplasias Colorrectales/metabolismo; Femenino; Estudios de Seguimiento; Regulación Neoplásica de la Expresión Génica; Humanos; Masculino; Persona de Mediana Edad; Pronóstico; Receptores Acoplados a Proteínas G/genética; Tasa de Supervivencia

Palabras clave

Colitis associated colorectal carcinoma; Crohn's disease; Inflammatory bowel disease; LGR5; Ulcerative colitis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenocarcinoma / Biomarcadores de Tumor / Colitis / Receptores Acoplados a Proteínas G / Carcinogénesis Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article

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