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Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.
Zhang, Ke; Miorin, Lisa; Makio, Tadashi; Dehghan, Ishmael; Gao, Shengyan; Xie, Yihu; Zhong, Hualin; Esparza, Matthew; Kehrer, Thomas; Kumar, Anil; Hobman, Tom C; Ptak, Christopher; Gao, Boning; Minna, John D; Chen, Zhijian; García-Sastre, Adolfo; Ren, Yi; Wozniak, Richard W; Fontoura, Beatriz M A.
  • Zhang K; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Makio T; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Dehghan I; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
  • Gao S; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Xie Y; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Zhong H; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Esparza M; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37235, USA.
  • Kehrer T; Department of Biological Sciences, Hunter College, New York, NY 10065, USA.
  • Kumar A; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Hobman TC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Ptak C; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Gao B; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
  • Minna JD; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
  • Chen Z; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
  • García-Sastre A; Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Ren Y; Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Wozniak RW; Departments of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Fontoura BMA; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sci Adv ; 7(6)2021 02.
Article en En | MEDLINE | ID: mdl-33547084
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Expresión Génica / Proteínas no Estructurales Virales / Factores de Virulencia / Interacciones Microbiota-Huesped / SARS-CoV-2 / COVID-19 Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Expresión Génica / Proteínas no Estructurales Virales / Factores de Virulencia / Interacciones Microbiota-Huesped / SARS-CoV-2 / COVID-19 Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article