Protective effects of NLRP3 inhibitor MCC950 on sepsis-induced myocardial dysfunction.

Li, S; Guo, Z; Zhang, Z Y

Li, S; Guo, Z; Zhang, Z Y.

Li S; Department of Liver Intensive Care Unit, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Guo Z; Department of Intensive Care Unit, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Zhang ZY; Department of Liver Intensive Care Unit, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

J Biol Regul Homeost Agents ; 35(1): 141-150, 2021.

Article en En | MEDLINE | ID: mdl-33550789

Asunto(s)

Cardiopatías/etiología; Sepsis; Animales; Caspasa 1; Furanos; Compuestos Heterocíclicos de 4 o más Anillos; Indenos; Proteína con Dominio Pirina 3 de la Familia NLR; Piroptosis; Ratas; Sepsis/complicaciones; Sepsis/tratamiento farmacológico; Sulfonamidas; Sulfonas

Palabras clave

MCC950; NLRP3/Caspase-1/IL-1ß pathway; inflammation; pyroptosis; sepsis-induced myocardial dysfunction

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sepsis / Cardiopatías Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

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