How strong is the warranty of a negative FFR? Comment on long-term outcome after deferred revascularization due to negative fractional flow reserve in intermediate coronary lesions by Weerts et al.

ABSTRACT

Outcomes of deferred PCI based on negative FFR are generally good. This study demonstrated deferred target lesion failure with FFR >0.80 in 7% and related it to coexistent risk factors, such as multivessel disease, diabetes, and SVG lesions. A negative FFR is only one variable on the continuum of ischemic risk, but in general provides an excellent prognostic tool.