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WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways.
Chen, Tianli; Li, Kangshuai; Liu, Zengli; Liu, Jialiang; Wang, Yue; Sun, Rongqi; Li, Zhipeng; Qiu, Bo; Zhang, Xiaoming; Ren, Guangli; Xu, Yunfei; Zhang, Zongli.
  • Chen T; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Li K; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Liu Z; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Liu J; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Wang Y; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Sun R; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Li Z; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Department of General Surgery, Shandong Second Provincial General Hospital, Shandong Provincial ENT Hospital, Jinan, China.
  • Qiu B; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Zhang X; Department of General Surgery, Linyi People's Hospital, Linyi, China.
  • Ren G; Department of General Surgery, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
  • Xu Y; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China. Electronic address: xuyunfei1988@126.com.
  • Zhang Z; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China. Electronic address: zzlzzl1900@163.com.
Mol Ther ; 29(6): 2134-2150, 2021 06 02.
Article en En | MEDLINE | ID: mdl-33601056
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Proto-Oncogénicas c-myc / Colangiocarcinoma / Péptidos y Proteínas de Señalización Intracelular / Subunidad alfa del Factor 1 Inducible por Hipoxia / Transición Epitelial-Mesenquimal Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Proto-Oncogénicas c-myc / Colangiocarcinoma / Péptidos y Proteínas de Señalización Intracelular / Subunidad alfa del Factor 1 Inducible por Hipoxia / Transición Epitelial-Mesenquimal Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article