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Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.
Saulle, Ernestina; Spinello, Isabella; Quaranta, Maria Teresa; Pasquini, Luca; Pelosi, Elvira; Iorio, Egidio; Castelli, Germana; Chirico, Mattea; Pisanu, Maria Elena; Ottone, Tiziana; Voso, Maria Teresa; Testa, Ugo; Labbaye, Catherine.
  • Saulle E; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
  • Spinello I; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
  • Quaranta MT; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
  • Pasquini L; Core Facilities, Istituto Superiore di Sanità, Rome, Italy.
  • Pelosi E; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Iorio E; Core Facilities, Istituto Superiore di Sanità, Rome, Italy.
  • Castelli G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Chirico M; Core Facilities, Istituto Superiore di Sanità, Rome, Italy.
  • Pisanu ME; Core Facilities, Istituto Superiore di Sanità, Rome, Italy.
  • Ottone T; Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Voso MT; Santa Lucia Foundation, I.R.C.C.S., Neuro-Oncohematology, Rome, Italy.
  • Testa U; Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Labbaye C; Santa Lucia Foundation, I.R.C.C.S., Neuro-Oncohematology, Rome, Italy.
Front Oncol ; 10: 621458, 2020.
Article en En | MEDLINE | ID: mdl-33614502
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Año: 2020 Tipo del documento: Article