Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research.

Andrysiak, Kalina; Stepniewski, Jacek; Dulak, Józef

Andrysiak, Kalina; Stepniewski, Jacek; Dulak, Józef.

Andrysiak K; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Stepniewski J; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Dulak J; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland. jozef.dulak@uj.edu.pl.

Pflugers Arch ; 473(7): 1061-1085, 2021 07.

Article en En | MEDLINE | ID: mdl-33629131

Asunto(s)

Corazón/fisiología; Células Madre Pluripotentes Inducidas/citología; Miocitos Cardíacos/citología; Animales; Desarrollo de Medicamentos/métodos; Humanos; Dispositivos Laboratorio en un Chip; Contracción Miocárdica/efectos de los fármacos; Contracción Miocárdica/fisiología

Palabras clave

3D structures; Body-on-a-chip; Cardiomyocytes; Cardiotoxicity; Drug research; EHT; Engineered heart tissue; Heart-on-a-chip; Organoids; Spheroids; Stem cells; hiPSC; hiPSC-CMs

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Miocitos Cardíacos / Células Madre Pluripotentes Inducidas / Corazón Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

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