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Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes.
Lugenbiel, Patrick; Govorov, Katharina; Syren, Pascal; Rahm, Ann-Kathrin; Wieder, Teresa; Wunsch, Maximilian; Weiberg, Nadine; Manolova, Emili; Gramlich, Dominik; Rivinius, Rasmus; Finke, Daniel; Lehmann, Lorenz H; Schweizer, Patrick A; Frank, Derk; El Tahry, Fadwa A; Bruehl, Claus; Heimberger, Tanja; Sandke, Steffi; Weis, Tanja; Most, Patrick; Schmack, Bastian; Ruhparwar, Arjang; Karck, Matthias; Frey, Norbert; Katus, Hugo A; Thomas, Dierk.
  • Lugenbiel P; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Govorov K; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Syren P; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Rahm AK; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Wieder T; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Wunsch M; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Weiberg N; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Manolova E; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Gramlich D; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Rivinius R; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Finke D; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Lehmann LH; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Schweizer PA; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Frank D; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, University of Heidelberg, Heidelberg, Germany.
  • El Tahry FA; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Bruehl C; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Heimberger T; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Sandke S; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Weis T; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Most P; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Schmack B; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Ruhparwar A; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Karck M; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
  • Frey N; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Katus HA; Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
  • Thomas D; HCR (Heidelberg Center for Heart Rhythm Disorders), Heidelberg, Germany.
Basic Res Cardiol ; 116(1): 13, 2021 02 25.
Article en En | MEDLINE | ID: mdl-33630168
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Fibrilación Atrial / Potenciales de Acción / Canales de Potasio / Miocitos Cardíacos / Epigénesis Genética / Histona Desacetilasa 2 / Atrios Cardíacos / Frecuencia Cardíaca Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Fibrilación Atrial / Potenciales de Acción / Canales de Potasio / Miocitos Cardíacos / Epigénesis Genética / Histona Desacetilasa 2 / Atrios Cardíacos / Frecuencia Cardíaca Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article