LvHemB1, a novel cationic antimicrobial peptide derived from the hemocyanin of Litopenaeus vannamei, induces cancer cell death by targeting mitochondrial voltage-dependent anion channel 1.

Liu, Shangjie; Aweya, Jude Juventus; Zheng, Liyuan; Zheng, Zhou; Huang, He; Wang, Fan; Yao, Defu; Ou, Tong; Zhang, Yueling

Liu, Shangjie; Aweya, Jude Juventus; Zheng, Liyuan; Zheng, Zhou; Huang, He; Wang, Fan; Yao, Defu; Ou, Tong; Zhang, Yueling.

Liu S; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, 515063, China.
Aweya JJ; Institute of Urology, The Affiliated Shenzhen Luohu Hospital of Shantou University Medical College, Shantou University, Shantou, 515063, China.
Zheng L; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, 515063, China.
Zheng Z; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, 515063, China.
Huang H; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, 515063, China.
Wang F; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, 515063, China.
Yao D; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, 515063, China.
Ou T; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, 515063, China.
Zhang Y; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, 515063, China.

Cell Biol Toxicol ; 38(1): 87-110, 2022 02.

Article en En | MEDLINE | ID: mdl-33630204

Asunto(s)

Neoplasias; Canal Aniónico 1 Dependiente del Voltaje; Péptidos Catiónicos Antimicrobianos/metabolismo; Péptidos Catiónicos Antimicrobianos/farmacología; Péptidos Antimicrobianos; Apoptosis; Proteínas Reguladoras de la Apoptosis/metabolismo; Hemocianinas/metabolismo; Hemocianinas/farmacología; Humanos; Potencial de la Membrana Mitocondrial; Mitocondrias/metabolismo; Simulación del Acoplamiento Molecular; Neoplasias/tratamiento farmacológico; Neoplasias/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Canal Aniónico 1 Dependiente del Voltaje/química; Canal Aniónico 1 Dependiente del Voltaje/metabolismo

Palabras clave

Anticancer; Antiproliferative effect; Apoptosis; Cationic antimicrobial peptide; Litopenaeus vannamei hemocyanin; Mitochondrial dysfunction

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canal Aniónico 1 Dependiente del Voltaje / Neoplasias Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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