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Lead-free MCP to improve coincidence time resolution and reduce MCP direct interactions.
Ota, R; Nakajima, K; Ogawa, I; Tamagawa, Y; Kwon, S I; Berg, E; Cherry, S R; Shimoi, H; Hasegawa, Y; Nishizawa, H; Shimano, K; Hasegawa, T.
  • Ota R; Central Research Laboratory, Hamamatsu Photonics K. K., Hamamatsu, Japan.
  • Nakajima K; Graduate School of Engineering, University of Fukui, Fukui, Japan.
  • Ogawa I; Graduate School of Engineering, University of Fukui, Fukui, Japan.
  • Tamagawa Y; Graduate School of Engineering, University of Fukui, Fukui, Japan.
  • Kwon SI; Department of Biomedical Engineering, University of California, Davis, CA, United States of America.
  • Berg E; Department of Biomedical Engineering, University of California, Davis, CA, United States of America.
  • Cherry SR; Department of Biomedical Engineering, University of California, Davis, CA, United States of America.
  • Shimoi H; Electron Tube Division, Hamamatsu Photonics K. K., Iwata, Japan.
  • Hasegawa Y; Electron Tube Division, Hamamatsu Photonics K. K., Iwata, Japan.
  • Nishizawa H; Electron Tube Division, Hamamatsu Photonics K. K., Iwata, Japan.
  • Shimano K; Electron Tube Division, Hamamatsu Photonics K. K., Iwata, Japan.
  • Hasegawa T; School of Allied Health Science, Kitasato University, Kitasato, Japan.
Phys Med Biol ; 66(6): 064006, 2021 03 17.
Article en En | MEDLINE | ID: mdl-33636710
ABSTRACT
Achieving direct imaging of the annihilation position of a positron on an event-by-event basis using an ultrafast detector would have a great impact on the field of nuclear medicine. Cherenkov emission is the most attractive physical phenomenon for realizing such an ultrafast timing performance. Moreover, a microchannel-plate photomultiplier tube (MCP-PMT) is one of the most promising photodetectors for fully exploiting the fast timing properties of Cherenkov emission owing to its excellent single photon time resolution of 25 ps full width at half maximum (FWHM). However, as the MCP structure generally contains a lead compound, the gamma rays frequently and directly interact with the MCP, resulting in the degradation of its timing performance and generation of undesirable side peaks in its coincidence timing histogram. To overcome this problem, we have developed a new MCP-PMT based on an MCP consisting of borosilicate glass, thus drastically reducing the probability of the photoelectric effect occurring in the MCP. To evaluate its insensitivity to gamma rays and its timing performance, a coincidence experiment was performed and showed that the probability of direct interactions was reduced by a factor of 3.4. Moreover, a coincidence time resolution of 35.4 ± 0.4 ps FWHM, which is equivalent to a position resolution of 5.31 mm, was obtained without any pulse height/area cut, improving to 28.7 ± 3.0 ps when selecting on the highest amplitude events by careful optimization of the voltage divider circuit of the new MCP-PMT. The timing performance of this new MCP-PMT presents an important step toward making direct imaging possible.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Dióxido de Silicio / Tomografía de Emisión de Positrones / Plomo Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Dióxido de Silicio / Tomografía de Emisión de Positrones / Plomo Idioma: En Año: 2021 Tipo del documento: Article