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Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFß/CTGF Axis.
Hinz, Nico; Baranowsky, Anke; Horn, Michael; Kriegs, Malte; Sibbertsen, Freya; Smit, Daniel J; Clezardin, Philippe; Lange, Tobias; Schinke, Thorsten; Jücker, Manfred.
  • Hinz N; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Baranowsky A; Center for Experimental Medicine, Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Horn M; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Kriegs M; University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Sibbertsen F; Mildred Scheel Cancer Career Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Smit DJ; Department of Radiotherapy & Radiation Oncology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Clezardin P; UCCH Kinomics Core Facility, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Lange T; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Schinke T; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Jücker M; INSERM, Research Unit UMR S1033, LyOS, Faculty of Medicine Lyon-Est, University of Lyon 1, 69372 Lyon, France.
Cells ; 10(2)2021 02 18.
Article en En | MEDLINE | ID: mdl-33670586
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Neoplasias de la Mama / Factor de Crecimiento Transformador beta / Receptor ErbB-2 / Proteínas Proto-Oncogénicas c-akt / Factor de Crecimiento del Tejido Conjuntivo / Receptores con Dominio Discoidina Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Neoplasias de la Mama / Factor de Crecimiento Transformador beta / Receptor ErbB-2 / Proteínas Proto-Oncogénicas c-akt / Factor de Crecimiento del Tejido Conjuntivo / Receptores con Dominio Discoidina Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article