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Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage.
Le Boiteux, Elisa; Court, Franck; Guichet, Pierre-Olivier; Vaurs-Barrière, Catherine; Vaillant, Isabelle; Chautard, Emmanuel; Verrelle, Pierre; Costa, Bruno M; Karayan-Tapon, Lucie; Fogli, Anne; Arnaud, Philippe.
  • Le Boiteux E; CNRS, Inserm, GReD, Université Clermont Auvergne, Clermont-Ferrand, France.
  • Court F; CNRS, Inserm, GReD, Université Clermont Auvergne, Clermont-Ferrand, France.
  • Guichet PO; INSERM-U1084, Poitiers, France.
  • Vaurs-Barrière C; Poitiers University, France.
  • Vaillant I; Department of Cancer Biology, Poitiers Hospital, France.
  • Chautard E; CNRS, Inserm, GReD, Université Clermont Auvergne, Clermont-Ferrand, France.
  • Verrelle P; CNRS, Inserm, GReD, Université Clermont Auvergne, Clermont-Ferrand, France.
  • Costa BM; Pathology Department, Jean Perrin Center, Clermont-Ferrand, France.
  • Karayan-Tapon L; INSERM, U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, France.
  • Fogli A; CIMB, INSERM U1196 CNRS UMR9187, Curie Institute, Orsay, France.
  • Arnaud P; Radiotherapy Department, Curie Institute, Paris, France.
Mol Oncol ; 15(8): 1995-2010, 2021 08.
Article en En | MEDLINE | ID: mdl-33720519
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Histonas / Genes Homeobox / Regiones Promotoras Genéticas / Metilación de ADN / Glioma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Histonas / Genes Homeobox / Regiones Promotoras Genéticas / Metilación de ADN / Glioma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article