Aortic aneurysm and aortic graft infection related to Mycobacterium bovis after intravesical Bacille Calmette-Guérin therapy-a case series.
BMC Surg
; 21(1): 138, 2021 Mar 17.
Article
en En
| MEDLINE
| ID: mdl-33731071
ABSTRACT
BACKGROUND:
So called "mycotic" aortic aneurysms account for only 0.7 to 1.3% of all aortic aneurysms and are commonly caused by Staphylococcus aureus and Salmonella species. Bacillus Calmette-Guérin (BCG), a live attenuated strain of Mycobacterium bovis, is part of the therapy of non-muscle-invasive bladder cancer (NMIBC). CASE PRESENTATION We report a case series of three patients with a mycobacterial graft infection related to BCG after surgical treatment of a presumed mycotic aortic aneurysm as an extremely rare complication after NMIBC treatment. All three patients developed aortic aneurysm after BCG instillation and subsequent mycobacterial graft infection.CONCLUSION:
Diagnosis requires a high degree of suspicion because of its nonspecific symptoms and imaging. The pathogen is not detected by standard microbiological testing. Treatment includes triple antimycobacterial therapy and radical surgical interventions. Graft preservation may be considered if no anastomosis is involved.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Aneurisma de la Aorta
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Neoplasias de la Vejiga Urinaria
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Aneurisma Infectado
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Vacuna BCG
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Inmunoterapia
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Mycobacterium bovis
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Infecciones por Mycobacterium
Límite:
Aged
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2021
Tipo del documento:
Article