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Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila.
Atilano, Magda L; Grönke, Sebastian; Niccoli, Teresa; Kempthorne, Liam; Hahn, Oliver; Morón-Oset, Javier; Hendrich, Oliver; Dyson, Miranda; Adams, Mirjam Lisette; Hull, Alexander; Salcher-Konrad, Marie-Therese; Monaghan, Amy; Bictash, Magda; Glaria, Idoia; Isaacs, Adrian M; Partridge, Linda.
  • Atilano ML; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, London, United Kingdom.
  • Grönke S; UK Dementia Research Institute at UCL, London, United Kingdom.
  • Niccoli T; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Kempthorne L; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, London, United Kingdom.
  • Hahn O; UK Dementia Research Institute at UCL, London, United Kingdom.
  • Morón-Oset J; UK Dementia Research Institute at UCL, London, United Kingdom.
  • Hendrich O; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom.
  • Dyson M; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Adams ML; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Hull A; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Salcher-Konrad MT; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, London, United Kingdom.
  • Monaghan A; UK Dementia Research Institute at UCL, London, United Kingdom.
  • Bictash M; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, London, United Kingdom.
  • Glaria I; UK Dementia Research Institute at UCL, London, United Kingdom.
  • Isaacs AM; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, London, United Kingdom.
  • Partridge L; UK Dementia Research Institute at UCL, London, United Kingdom.
Elife ; 102021 03 19.
Article en En | MEDLINE | ID: mdl-33739284
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Expansión de las Repeticiones de ADN / Drosophila melanogaster / Demencia Frontotemporal / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Insulina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Expansión de las Repeticiones de ADN / Drosophila melanogaster / Demencia Frontotemporal / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Insulina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article