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Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.
Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins, Amy L; Vizioli, Maria Grazia; Habiballa, Leena; Saretzki, Gabriele; Evans, Shane A; Salmonowicz, Hanna; Hruby, Adam; Geh, Daniel; Pavelko, Kevin D; Dolan, David; Reeves, Helen L; Grellscheid, Sushma; Wilson, Colin H; Pandanaboyana, Sanjay; Doolittle, Madison; von Zglinicki, Thomas; Oakley, Fiona; Gallage, Suchira; Wilson, Caroline L; Birch, Jodie; Carroll, Bernadette; Chapman, James; Heikenwalder, Mathias; Neretti, Nicola; Khosla, Sundeep; Masuda, Claudio Akio; Tchkonia, Tamar; Kirkland, James L; Jurk, Diana; Mann, Derek A; Passos, João F.
  • Lagnado A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Leslie J; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Ruchaud-Sparagano MH; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Victorelli S; Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Hirsova P; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Ogrodnik M; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Collins AL; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Vizioli MG; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Habiballa L; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Saretzki G; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Evans SA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Salmonowicz H; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Hruby A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Geh D; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Pavelko KD; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Dolan D; Ageing Research Laboratories, Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Reeves HL; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.
  • Grellscheid S; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • Wilson CH; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Pandanaboyana S; Ageing Research Laboratories, Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Doolittle M; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  • von Zglinicki T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Gallage S; Department of Immunology and Immune Monitoring Core, Mayo Clinic, Rochester, MN, USA.
  • Wilson CL; Computational Biology Unit, University of Bergen, Bergen, Norway.
  • Birch J; Newcastle University Translational and Clinical Research Institute, Liver Unit, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Carroll B; Computational Biology Unit, University of Bergen, Bergen, Norway.
  • Chapman J; Department of Biosciences, Durham University, Durham, UK.
  • Heikenwalder M; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Neretti N; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Khosla S; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Masuda CA; Ageing Research Laboratories, Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Tchkonia T; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Kirkland JL; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Jurk D; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Mann DA; Ageing Research Laboratories, Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Passos JF; School of Biochemistry, University of Bristol, Bristol, UK.
EMBO J ; 40(9): e106048, 2021 05 03.
Article en En | MEDLINE | ID: mdl-33764576

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tetracloruro de Carbono / Especies Reactivas de Oxígeno / Lesión Pulmonar Aguda / Acortamiento del Telómero / Neutrófilos Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tetracloruro de Carbono / Especies Reactivas de Oxígeno / Lesión Pulmonar Aguda / Acortamiento del Telómero / Neutrófilos Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article