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Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.
Hwang, Yu Jin; Hyeon, Seung Jae; Kim, Younghee; Lim, Sungsu; Lee, Min Young; Kim, Jieun; Londhe, Ashwini M; Gotina, Lizaveta; Kim, Yunha; Pae, Ae Nim; Cho, Yong Seo; Seong, Jihye; Seo, Hyemyung; Kim, Yun Kyung; Choo, Hyunah; Ryu, Hoon; Min, Sun-Joon.
  • Hwang YJ; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Hyeon SJ; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Kim Y; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Lim S; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, KIST, Seoul, Republic of Korea.
  • Lee MY; Institute for Systems Biology, Seattle, WA, USA.
  • Kim J; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Londhe AM; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, KIST, Seoul, Republic of Korea.
  • Gotina L; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea.
  • Kim Y; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, KIST, Seoul, Republic of Korea.
  • Pae AN; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea.
  • Cho YS; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Seong J; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, KIST, Seoul, Republic of Korea.
  • Seo H; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea.
  • Kim YK; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Choo H; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea.
  • Ryu H; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, KIST, Seoul, Republic of Korea.
  • Min SJ; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea.
J Enzyme Inhib Med Chem ; 36(1): 856-868, 2021 Dec.
Article en En | MEDLINE | ID: mdl-33771089
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Heterocromatina / N-Metiltransferasa de Histona-Lisina / Enfermedad de Huntington / Modelos Animales de Enfermedad / Inhibidores Enzimáticos / Neuronas Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Heterocromatina / N-Metiltransferasa de Histona-Lisina / Enfermedad de Huntington / Modelos Animales de Enfermedad / Inhibidores Enzimáticos / Neuronas Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article