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Immunotherapy combined with high- and low-dose radiation to all sites leads to complete clearance of disease in a patient with metastatic vaginal melanoma.
Sezen, Duygu; Patel, Roshal R; Tang, Christine; Onstad, Michaela; Nagarajan, Priyadharsini; Patel, Sapna P; Welsh, James W; Lin, Lilie L.
  • Sezen D; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Radiation Oncology, Koc University School of Medicine, Istanbul, Turkey.
  • Patel RR; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Albany Medical College, Albany, NY, USA.
  • Tang C; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA.
  • Onstad M; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Nagarajan P; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Patel SP; Department of Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Welsh JW; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lin LL; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: lllin@mdanderson.org.
Gynecol Oncol ; 161(3): 645-652, 2021 06.
Article en En | MEDLINE | ID: mdl-33795130
ABSTRACT
A 73-year-old woman with metastatic vaginal mucosal melanoma that had progressed on ipilimumab and nivolumab experienced clinical and radiographic complete response to dual checkpoint inhibitor immunotherapy given in combination with high-dose plus low-dose radiation. General characteristics and treatment options in this disease are highlighted.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Uretrales / Neoplasias Vaginales / Melanoma Límite: Aged / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Uretrales / Neoplasias Vaginales / Melanoma Límite: Aged / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article