Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response.

Hlavác, Viktor; Václavíková, Radka; Brynychová, Veronika; Ostasov, Pavel; Kozevnikovová, Renata; Kopecková, Katerina; Vrána, David; Gatek, Jirí; Soucek, Pavel

Hlavác, Viktor; Václavíková, Radka; Brynychová, Veronika; Ostasov, Pavel; Kozevnikovová, Renata; Kopecková, Katerina; Vrána, David; Gatek, Jirí; Soucek, Pavel.

Hlavác V; Toxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Václavíková R; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, 301 00 Pilsen, Czech Republic.
Brynychová V; Toxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Ostasov P; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, 301 00 Pilsen, Czech Republic.
Kozevnikovová R; Toxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Kopecková K; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, 301 00 Pilsen, Czech Republic.
Vrána D; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, 301 00 Pilsen, Czech Republic.
Gatek J; Department of Oncosurgery, MEDICON, 140 00 Prague, Czech Republic.
Soucek P; Department of Oncology, Second Faculty of Medicine, Charles University and Motol University Hospital, 150 00 Prague, Czech Republic.

Int J Mol Sci ; 22(6)2021 Mar 10.

Article en En | MEDLINE | ID: mdl-33802237

Asunto(s)

Neoplasias de la Mama; Sistema Enzimático del Citocromo P-450; Variación Genética; Terapia Neoadyuvante; Proteínas de Neoplasias; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/enzimología; Neoplasias de la Mama/genética; Neoplasias de la Mama/mortalidad; Sistema Enzimático del Citocromo P-450/genética; Sistema Enzimático del Citocromo P-450/metabolismo; Supervivencia sin Enfermedad; Femenino; Humanos; Persona de Mediana Edad; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Tasa de Supervivencia

Palabras clave

breast cancer; cytochrome P450; next-generation sequencing; prognosis; response; survival; therapy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Variación Genética / Neoplasias de la Mama / Terapia Neoadyuvante / Sistema Enzimático del Citocromo P-450 / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Año: 2021 Tipo del documento: Article

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