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Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential.
Harada, Kosuke; Kohara, Hiroshi; Yukawa, Tomoya; Matsumiya, Kouta; Shinozawa, Tadahiro.
  • Harada K; Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Kohara H; Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Yukawa T; Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, 35 Landsdowne Street, Cambridge, MA 02139, USA.
  • Matsumiya K; Drug Metabolism & Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Shinozawa T; Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: tadahiro.shinozawa@takeda.com.
Toxicol In Vitro ; 74: 105159, 2021 Aug.
Article en En | MEDLINE | ID: mdl-33823239
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Analíticos de Alto Rendimiento / Activación Metabólica / Glutatión Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Analíticos de Alto Rendimiento / Activación Metabólica / Glutatión Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article