Solubilization and thermodynamic properties of simvastatin in various micellar solutions of different non-ionic surfactants: Computational modeling and solubilization capacity.

Shakeel, Faiyaz; Alshehri, Sultan; Ibrahim, Mohamed A; Altamimi, Mohammad; Haq, Nazrul; Elzayat, Ehab M; Shazly, Gamal A

Shakeel, Faiyaz; Alshehri, Sultan; Ibrahim, Mohamed A; Altamimi, Mohammad; Haq, Nazrul; Elzayat, Ehab M; Shazly, Gamal A.

Shakeel F; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Alshehri S; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ibrahim MA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Altamimi M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Haq N; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Elzayat EM; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Shazly GA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

PLoS One ; 16(4): e0249485, 2021.

Article en En | MEDLINE | ID: mdl-33831070

Asunto(s)

Micelas; Modelos Moleculares; Simvastatina/química; Tensoactivos/química; Conformación Molecular; Polietilenglicoles/química; Solubilidad; Solventes/química; Termodinámica; Agua/química

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tensoactivos / Modelos Moleculares / Simvastatina / Micelas Idioma: En Año: 2021 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tensoactivos / Modelos Moleculares / Simvastatina / Micelas Idioma: En Año: 2021 Tipo del documento: Article